IBANDRONATE SODIUM PROPYLENE GLYCOL SOLVATE AND PROCESSES FOR THE PREPARATION THEREOF
摘要
<p>Ibandronate sodium and propylene glycol readily forms a free-flowing crystalline solvate. The novel solvate is non-hygroscopic, free-flowing, chemically and polymorphically stable, and easily dried even on industrial scale. Thus, it is particularly suitable for pharmaceutical applications. A process for preparing said novel solvate is further disclosed. Formula (I).</p>