ASPARTYL PROTEASE INHIBITORS CONTAINING A TRICYCLIC RING SYSTEM

摘要

Disclosed are compounds of Formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof or wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, R<SUP>14</SUP>, W, V, X, Y, A and b are as described above in the specification. Also disclosed is a method of inhibiting aspartyl protease, methods of treating cardiovascular diseases, cognitive diseases, neurodegenerative diseases, and other biological processes and indications. Combination treatments and compositions are also disclosed.