HADRON TREATMENT PLANNING WITH ADEQUATE BIOLOGICAL WEIGHTING
摘要
Treatment planning methods are provided that determine the variability of relative biological effectiveness (RBE) along a beam line and calculate, among other things, what intensity of hadron beam such as a proton or a carbon ion beam should be applied to achieve a desired biological dose at treatment site of a patient afflicted with a medical condition. Typically, three or four RBE values at three or four corresponding spacially- dispersed intervals along the beam line are calculated. In one embodiment, two RBE values for the spread-out Bragg peak (SOBP) region of the treatment site; one for the proximal section and one for the declining distal section is calculated. A third and different RBE value may be determined for the distal edge region of the SOBP. A fourth value may also be calculated for a pre-SOBP region.
申请公布号
WO2007126782(A3)
申请公布日期
2008.06.19
申请号
WO2007US07520
申请日期
2007.03.27
申请人
HAMPTON UNIVERSITY;KEPPEL, CYNTHIA, E.;BRITTEN, RICHARD, A.;NAZARYAN, VAHAGN, R.
发明人
KEPPEL, CYNTHIA, E.;BRITTEN, RICHARD, A.;NAZARYAN, VAHAGN, R.