发明名称 |
PROCESS FOR STABILIZING FAMOTIDINE |
摘要 |
The present invention concerns the pharmaceutical industry, and more specifically the pharmaceutical industry involved in manufacturing products from famotidine. The present invention describes a method for stabilizing a H2 receptor inhibitor, such as famotidine, in an alkaline pH by means of a microencapsulation process using wax or polymeric products, such as microcrystalline wax, montan wax, ozokerite wax, chitosan or sodium alginate, as the materials which form the film. The advantages of the present invention with respect to the processes of the prior art are that its application makes it possible to produce a famotidine composition which is more resistant to the medium of the composition in which it is located and the effects which the composition might have on the digestive tract, particularly when this substance is included in a composition containing alkaline antacid. |
申请公布号 |
WO2008039052(A3) |
申请公布日期 |
2008.06.19 |
申请号 |
WO2007MX00108 |
申请日期 |
2007.09.24 |
申请人 |
ESPINOZA ABDALA, LEOPOLDO DE JESUS;GARCIA ARMANTA, MARIA ELENA;ALVAREZ OCHOA, VICTOR GUILLERMO;SANTOS MURILLO, JOSEFINA |
发明人 |
ESPINOZA ABDALA, LEOPOLDO DE JESUS;GARCIA ARMANTA, MARIA ELENA;ALVAREZ OCHOA, VICTOR GUILLERMO;SANTOS MURILLO, JOSEFINA |
分类号 |
A61K9/50;A61K31/426;A61K47/30 |
主分类号 |
A61K9/50 |
代理机构 |
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主权项 |
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地址 |
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