发明名称 TABLET DISINTEGRATED IN BUCCAL CAVITY
摘要 <P>PROBLEM TO BE SOLVED: To easily prepare a tablet soluble in buccal cavity having appropriate disintegrating property and solubility and appropriate strength not to disintegrate during manufacturing and storage. <P>SOLUTION: This tablet is prepared by tableting under a pressure of about 3-160 Kg/cm<SP>2</SP>a mixture containing medicinal components such as a vitamin, a digestive medicine, and an antipyretic demulcent antiphlogistic agent, at least one water-soluble saccharide selected from the group consisting of xylitol and erythritol, and water to wet the surface of the saccharide, and drying. The quantity of the medicinal component is about 0.05-90 wt.% of the mixture, that of the saccharide is about 10-90 wt.% of the mixture, and the water is contained about 0.3-10 wt.% of the mixture. The tablet soluble in buccal cavity having a porous structure with a porosity of 20-80% can be obtained by the above method. <P>COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2008133294(A) 申请公布日期 2008.06.12
申请号 JP20080010949 申请日期 2008.01.21
申请人 TAKEDA CHEM IND LTD 发明人 MAKINO TADASHI;YAMADA MASAYUKI;KIKUTA JUNICHI
分类号 A61K47/10;A61K9/20;A61K31/07;A61K31/09;A61K31/122;A61K31/137;A61K31/138;A61K31/166;A61K31/167;A61K31/198;A61K31/352;A61K31/355;A61K31/375;A61K31/4402;A61K31/4415;A61K31/46;A61K31/4741;A61K31/485;A61K31/51;A61K31/522;A61K31/525;A61K31/5513;A61K31/64;A61K31/714;A61K36/00 主分类号 A61K47/10
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