| 摘要 |
The present invention relates to compositions for the modulation of infla mmation in connective tissues in humans and animals and the modulation of ma rkers of such inflammation, including COX-2, TNF-.alpha., IL- 1.beta., iNOS, p38, and chemokines, comprising any or all of anabolic, anti-catabolic, ant i-oxidant and analgesic agents, including aminosugars, S-adenosylmethionine, arachadonic acid, GAGs, including pentosan, collagen type II, tetracyclines or tetracycline-like compounds, diacerin, super oxide dismutase, L-ergothio neine, methylsulfanylmethane, one or more avocado/soybean unsaponifiables, a nd an analgesic, e.g., acetaminophen, and to methods of treating humans and animals by administration of these novel compositions to humans and animals in need thereof.
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