发明名称 INHIBITORS OF AKT ACTIVITY
摘要 The instant invention provides for substituted naphthyridine compounds th at inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for comp ositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
申请公布号 CA2670760(A1) 申请公布日期 2008.06.12
申请号 CA20072670760 申请日期 2007.12.03
申请人 BANYU PHARMACEUTICAL CO., LTD.;MERCK & CO., INC. 发明人 WANG, JIABING;SANDERSON, PHILIP E.;ONOZAKI, YU;OGINO, YOSHIO;LIQUORI, MICHAEL E.;LAYTON, MARK E.;KELLY, MICHAEL J., III
分类号 C07D401/04;A61K31/4353;A61P35/00;C07D401/06;C07D403/04;C07D403/06;C07D407/04;C07D409/04;C07D413/04;C07D417/04;C07D471/14 主分类号 C07D401/04
代理机构 代理人
主权项
地址