| 摘要 |
The invention relates to a compound of the following general formula (III):
wherein:
R 1 and R 2 each are one or more independent substituents selected from the group consisting of hydrogen, C1-C5 alkyl, C2-C5 alkenyl, C3-C5 cycloalkyl, C1-C5 alkoxy, C2-C5 alkynyl, halogen, C1-C5 haloalkyl, alkylamino, phenyl, nitro and carboxyl;
R 3 is selected from the group consisting of amino, C1-C5 substituted amino and CH 2 ;
n and m are independently an integer of from 0-5;
or a pharmaceutically acceptable salt of such compound;
a compound of the following general formula (IV):
wherein:
R 1 and R 2 each are one or more independent substituents selected from the group consisting of hydrogen, C1-C5 alkyl, C2-C5 alkenyl, C3-C5 cycloalkyl, C1-C5 alkoxy, C2-C5 alkynyl, halogen, C1-C5 haloalkyl, alkylamino, phenyl, nitro and ca rboxyl;
R 3 and R 4 each are independent and selected from the group consisting of hydrogen and C1-C5 alkyl;
n is an integer of from 1 to 5;
or a pharmaceutically acceptable salt of such compound;
a compound of the following general formula (V):
wherein:
R 1 and R 2 each are one or more independent substituents selected from the group consisting of hydrogen, C1-C5 alkyl, C2-C5 alkenyl, C3-C5 cycloalkyl, C1-C5 alkoxy, C2-C5 alkynyl, halogen, C1-C5 haloalkyl, alkylamino, phenyl, nitro and carboxyl;
R 3 is selected from hydrogen and C1-C5 alkyl;
R 4 is selected from hydrogen and C1-C5 alkyl;
n is an integer of from 1 to 5 inclusive;
or a pharmaceutically acceptable salt of such compound; and
a compound of the following general formula (VI):
wherein:
R 1 and R 2 each are one or more independent substituents selected from the group consisting of hydrogen, C1-C5 alkyl, C2-C5 alkenyl, C3-C5 cycloalkyl, C1-C5 alkoxy, C2-C5 alkynyl, halogen, C1-C5 haloalkyl, alkylamino, phenyl, nitro and carboxyl;
R3 and R4 each are independent and selected from hydrogen and C1-C5 alkyl;
n is an integer of from 1 to 5 inclusive;
or a pharmaceutically acceptable salt of such compound. Also compositions comprising the compounds III-VI as well as uses of said compounds.
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