发明名称 |
CHEMILUMINESCENT ELECTRON-RICH ARYL-SUBSTITUTED 1,2-DIOXETANES |
摘要 |
Chemiluminescent electron-rich aryl-substituted 1,2-dioxetane compounds are disclosed in which the aryl group is polysubstituted with suitable electron-donating groups such that the light-emitting pattern of the molecule results in a very high luminescent count, thus providing for a sensitive and precise assay for haptens, analyte s, polynucleotides and the like. These substituted aryl-containing 1,2-dioxetane compounds can be used as direct labels in an immunoassay or when derivatized with an appropriate leaving group, can be used as a substrate for an enzyme immunoassay. The unusual chemiluminescence of the compounds allows the timing of the luminescent reaction to be exactly controlled.
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申请公布号 |
CA2146669(C) |
申请公布日期 |
2008.06.10 |
申请号 |
CA19932146669 |
申请日期 |
1993.10.26 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
WANG, NAI-YI;HU, ROGER C. |
分类号 |
C07F7/18;C07D321/00;C07D493/04;C07F9/655;C07F9/6561;C12Q1/34;C12Q1/42;C12Q1/68;C12Q1/70;G01N33/53;G01N33/533;G01N33/58 |
主分类号 |
C07F7/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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