发明名称 4,5-dihydronaphtho[1,2-b]thiophene derivative
摘要 A 4,5-dihydronaphtho[1,2-b]thiophene derivative expressed by the formula: (wherein R<SUP>1 </SUP>is a C<SUB>1 </SUB>to C<SUB>10 </SUB>1-hydroxyalkyl group or a C<SUB>1 </SUB>to C<SUB>10 </SUB>acyl group, and R<SUP>2 </SUP>and R<SUP>3 </SUP>separately substitute in the 6-, 7-, 8-, or 9-positions, and are each independently a hydrogen atom, a halogen atom, a C<SUB>1 </SUB>to C<SUB>10 </SUB>alkyl group, a hydroxy group, a C<SUB>1 </SUB>to C<SUB>10 </SUB>alkoxy group, a C<SUB>1 </SUB>to C<SUB>5 </SUB>alkenyloxy group, a C<SUB>1 </SUB>to C<SUB>5 </SUB>alkynyloxy group, a benzyloxy group, or the like, provided that when R<SUP>1 </SUP>is an acyl group and R<SUP>2 </SUP>is a hydrogen atom, then R<SUP>3 </SUP>is neither a hydrogen atom nor an acetyl group), or a pharmaceutically acceptable salt thereof This is a novel compound that is effective in reducing triglyceride levels in the liver and reducing blood glucose levels.
申请公布号 US7384974(B2) 申请公布日期 2008.06.10
申请号 US20040566572 申请日期 2004.07.30
申请人 TAISHA PHARMACEUTICAL CO., LTD. 发明人 TAGUCHI MINORU;SUZUKI RYO;MIKAMI AYAKO
分类号 A61K31/381;A61P3/04;A61P3/06;A61P3/10;C07D319/18;C07D333/74;C07D495/04;C07D495/14 主分类号 A61K31/381
代理机构 代理人
主权项
地址