发明名称 CIS-CYCLOHEXYL SUBSTITUTED PYRIMIDINONE DERIVATIVES
摘要 Cis-cyclohexyl substituted pyrimidinone derivatives are provided, of Form ula (I) wherein variables are as described herein. Such compounds are ligand s that may be used to modulate specific receptor activity in vivo or in vitr o, and are particularly useful in the treatment of conditions associated wit h pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using su ch compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
申请公布号 CA2668579(A1) 申请公布日期 2008.06.05
申请号 CA20072668579 申请日期 2007.11.05
申请人 NEUROGEN CORPORATION 发明人 ZHENG, XIAOZHANG;BLUM, CHARLES A.;GHOSH, MANUKA;ZHANG, XUECHUN;MARTINEZ, ISAMIR
分类号 C07D473/34;A61K31/519;A61K31/522;A61P3/04;A61P11/14;A61P13/10;A61P25/02;A61P25/06;A61P35/04;C07D471/04;C07D495/04;C07D513/04 主分类号 C07D473/34
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