发明名称 |
ELONGASE GENE AND USES THEREOF |
摘要 |
The subject invention relates to the identification of a gene involved in the elongation of polyunaturated fatty acids containing unsaturation at the carbon 9 position (i.e., "?9-elongase") and to uses thereof. In particular, ?9-elongase may be utilized, for example, in the conversion of linoleic acid (LA, 18:2n-6) to eicosadienoic acid (EDA, 20:2n-6). The production of dihomo-y-linolenic acid (DGLA, 20:3n-6) from eicosadienoic acid (EDA, 20:2n-6), and arachidonic acid (AA, 20:4n-6) from dihomo-y-linolenic acid (DGLA, 20:3n-6) is then catalyzed by ?8-desaturase and ?5-desaturase, respectively. AA or polyunsafurated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics. |
申请公布号 |
WO2008064096(A2) |
申请公布日期 |
2008.05.29 |
申请号 |
WO2007US84902 |
申请日期 |
2007.11.16 |
申请人 |
ABBOTT LABORATORIES;DAS, TAPAS;MUKERJI, PRADIP;KRISHNAN, PADMAVATHY;LEONARD, AMANDA, E.;PEREIRA, SUZETTE, L. |
发明人 |
DAS, TAPAS;MUKERJI, PRADIP;KRISHNAN, PADMAVATHY;LEONARD, AMANDA, E.;PEREIRA, SUZETTE, L. |
分类号 |
C07K14/43 |
主分类号 |
C07K14/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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