The present invention provides methods for identifying metastases by detecting nucleic acid hypermethylation of one or more genes in one or more samples, and in particular in the lymph nodes. The invention further relates to DNA methylation as a predictor of disease recurrence and patient prognosis, specifically in the field of cancer biology.
申请公布号
WO2008063655(A2)
申请公布日期
2008.05.29
申请号
WO2007US24308
申请日期
2007.11.20
申请人
THE JOHNS HOPKINS UNIVERSITY;BROCK, MALCOLM, V.;BAYLIN, STEPHEN;HERMAN, JAMES, G.
发明人
BROCK, MALCOLM, V.;BAYLIN, STEPHEN;HERMAN, JAMES, G.