发明名称 |
PROCESS FOR THE PREPARATION OF AMINO ALCOHOLS AND DERIVATIVES THEREOF |
摘要 |
<p>Microorganisms (A), or their enzymatic extracts, able to utilise cyclopentene derivatives (VII) as sole carbon (or carbon and nitrogen) source are new. R1 = 1-4C alkyl or alkoxy, or aryl or aryloxy. Also new are (1) N-acetylamino-alcohol hydrolases (NAAH) from (A) able to hydrolyse (VII), and their functionally equivalent variants or mutants; (2) production of (1R,4S) and/or (1S,4R)-1-amino-4-hydroxymethyl-2-cyclopentene (II), or their derivatives N-substituted by COR1, by reacting (VII) with at least one of (A), its enzymatic extract, NAAH and penicillin G acylase.</p> |
申请公布号 |
HU226141(B1) |
申请公布日期 |
2008.05.28 |
申请号 |
HU19990002963 |
申请日期 |
1997.05.30 |
申请人 |
LONZA AG. |
发明人 |
BERNEGGER-EGLI, CHRISTINE DR;BIRCH, OLWEN MARY DR;BOSSARD, PIERRE DR;BRIEDEN, WALTER;BRUX, FRANK;BURGDORF, KNUT;DUC, LAURENT DR;ETTER, KAY-SARAH;GUGGISBERG, IVES;SAUTER, MARTIN;URBAN, EVA MARIA |
分类号 |
C12N1/20;C07C215/42;C07C231/08;C07C233/23;C07D209/52;C12N1/21;C12N9/80;C12P13/00;C12P13/02;C12P41/00;C12R1/01 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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