| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to the new method of producing formerly unknown 1-(pyrimidine-2-il)propane-2-on of the general formula wherein R designates every time the C1-C10 alkyl group. The method consists in that the reaction of malone diimidate is carried out with the general formula , wherein R has the above-stated magnitudes, with dikenete of the formula . It is preferable to use malone diimidate (II) produced in situ from is appropriate salt and base. Here, the salt of used malone diimidate (II) is dihydrochloride, and tertiary amine. The preferable malone diimidate of the formula (II) is dimethyl malone diimidate. ^ EFFECT: new compounds feature useful biological properties. ^ 6 cl, 2 ex |
