NEW CRYSTALLINE FORM OF ENTACAPONE AND PROCESS FOR ITS PREPARATION

摘要

The invention relates to a new stable crystalline form of Entacapone, denominated Form F. It also relates to the process for preparing it and to the pharmaceutically acceptable composition that comprises it. The process comprises dissolving by heating the Entacapone product in an organic solvent; adding the solution obtained in the preceding step to a previously heated anti-solvent; cooling the suspension obtained; and isolating the precipitate so obtained by filtration, and then drying the product obtained until constant weight.