SEAWEED-DERIVED IMMUNOSTIMULANT AND ANTIINFLAMMATORY AGENT

摘要

It is intended to provide a natural product-derived antiinflammatory agent with a high safety. A pharmaceutical composition comprising a cyclooxygenase-2 (COX-2) inhibitor which is derived from a seaweed belonging to the brown algae, contains magnesium and has a molecular weight of from 250 to 500 is provided. The seaweed belonging to the brown algae is preferably a seaweed belonging to the genus Durvillea, Nemacystus, Ceratophyllum, Lessonia, Ecklonia, Macrocystis, Fucus, or Ascophyllum, and particularly preferably a seaweed belonging to the genus Durvillea or Nemacystus. A component derived from a seaweed belonging to the genus Durvillea selectively inhibits COX-2.