发明名称 4-PYPERAZINYL-BENZEN-SULFANYLINDOLES WITH AFFINITY TO 5-HT6 RECEPTOR
摘要 FIELD: medicine; pharmacology. ^ SUBSTANCE: invention is related to 4-pyperazinyl-benzen-sulfanylindols with the general formula I , where: R1 and R2 each independently means hydrogen, halogen, alcoxy, R3 and R4 each independently means hydrogen, halogen, alkyl, n is equal to 0 to 4, R6 in each particular case means hydrogen or halogen, R7 and R8 each means hydrogen, R9 means hydrogen, alkyl, or individual isomer, racemic or non-racemic mixture of isomers or their pharmaceutically acceptable salt or solvate. The pharmaceutical compositions are described based on compound I. ^ EFFECT: compounds can be efficiently used in treatment of certain diseases of central nervous system. ^ 14 cl, 1 tbl, 4 ex
申请公布号 RU2324693(C2) 申请公布日期 2008.05.20
申请号 RU20050115115 申请日期 2003.10.13
申请人 F.KHOFFMANN-LJA ROSH AG 发明人 KLARK ROBIN DUGLAS;KHARRIS RALF N'JU III;REPKE DEJVID BRJUS
分类号 C07D403/12;A61K31/496;A61P25/00;C07D209/08;C07D209/30 主分类号 C07D403/12
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