发明名称 |
Human Rgr oncogene and truncated transcripts thereof detected in T cell malignancies, antibodies to the encoded polypeptides and methods of use |
摘要 |
Naturally-occurring variants of human Rgr oncogene protein, in particular, abnormally truncated variants found in T cell malignancies, as well as the human Rgr protein are encompassed by the present invention. Also included are antibodies thereto and nucleic acid molecules encoding human Rgr protein and naturally-occurring variants thereof. The present invention further provides methods for diagnosing and treating T cell malignancies associated with abnormally truncated transcripts of human rgr oncogene and/or abnormal truncation of human Rgr protein.
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申请公布号 |
US7374935(B2) |
申请公布日期 |
2008.05.20 |
申请号 |
US20030625471 |
申请日期 |
2003.07.23 |
申请人 |
NEW YORK UNIVERSITY |
发明人 |
PELLICER ANGEL;LEONARDI PETER;INGHIRAMI GIORGIO |
分类号 |
C07H21/00;C07H21/02;C07H21/04;C07K14/82;C12N5/10;C12N15/00 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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