| 摘要 |
The present invention relates to compounds of formula I wherein R<SUP>1 </SUP>is selected from the group consisting of hydrogen and lower alkyl; each R<SUP>2 </SUP>is independently selected from the group consisting of hydrogen and lower alkyl; each R<SUP>3 </SUP>is independently selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, phenyloxy, benzyloxy, halogen and lower alkyl substituted by halogen; X is selected from the group consisting of -CH<SUB>2</SUB>-, -CH- and -O-; Y is selected from the group consisting of -CH<SUB>2</SUB>-, -CH- and a bond with the proviso that, when X is -O-, Y may not be a bond; Z is selected from the group consisting of -CH<SUB>2</SUB>- and -CH-; m is 0, 1 or 2; and n is 0, 1 or 2; and to pharmaceutically-acceptable acid addition salts of such compounds. The invention relates also to processes for preparing such compounds, compositions comprising such a compound or a pharmaceutically-acceptable acid addition salt thereof, and a method of treating a disease or disorder in a patient comprising administering such a compound, or pharmaceutically-acceptable acid addition salt thereof, to a patient in need of such treatment.
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