SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION
摘要
<p>The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened orhedgehog activity.</p>
申请公布号
WO2008057468(A1)
申请公布日期
2008.05.15
申请号
WO2007US23228
申请日期
2007.11.02
申请人
WYETH;CURIS, INC.;BRUNTON, SHIRLEY, ANN;GUICHERIT, OIVIN, M.;KRUSE, LAWRENCE, I.
发明人
BRUNTON, SHIRLEY, ANN;GUICHERIT, OIVIN, M.;KRUSE, LAWRENCE, I.