摘要 |
The invention provides a dosage form, comprising a melt-processed mixture of (a) a pharmaceutically effective amount of imatinib or a salt thereof, (b) at least one polymeric binder, and (c) at least one pharmaceutically acceptable non-ionic surfactant. The invention provides imatinib dosage forms with high drug loading which can be prepared in a simple and efficient manner, imatinib dosage forms from which the active principle is released in an essentially pH-independent fashion, and extended release imatinib dosage forms. |
申请人 |
ABBOTT GMBH & CO. KG;NOVARTIS AG |
发明人 |
BREITENBACH, JOERG;STEIGER, NORBERT;HACH, HARALD;WESTEDT, ULRICH;KNOBLOCH, MARTIN;ALTENBURGER, RALF;LOGGIA, NICOLETTA;OGORKA, JOERG |