Monoklonalt museantistof (5c8) genkender et menneskeligt glycoprotein på overfladen af T-lymfocytter

摘要

This invention provides a monoclonal antibody capable of binding to a protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC Accession No. HB 10916. This invention also provides an isolated protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC Accession No. HB 10916. This invention further provides an isolated nucleic acid molecule encoding a protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC No. HB 10916. This invention also provides a human CD4<-> T cell leukemia cell line designated D1.1 having ATCC Accession No. CRL 10915 capable of constitutively providing cotnact-dependent helper function to B cells.