摘要 |
A high-content injection for intravenous drip which is prepared by adding an acidic pH regulator to an aqueous suspension containing 4-(N-(4-morpholin-4-yl)butyl)carbamoylmethyl)-5,6,7, 8-tetrahydrophthalazin-1(2H)-one (Compound A) and dissolving it therein followed by, if necessary, adjusting the pH value by using a basic pH regulator. Because of being stable to light and heat, this injection is a highly useful preparation. It is preferable to adjust the pH value of the injection to 3 to 7. The concentration of the compound A is preferably from 50 mg/mL to 300 mg/mL and the viscosity of the injection is preferably from 1 mPa.s to 4 mPa.s.
|