COMPOSITIONS AND METHOD FOR MONITORING BCR-ABL EXPRESSION

摘要

The invention provides the parameters required to make high quality standards for use in monitoring bcr-abl expression in subjects and determine whether a patient with Ph+CML has achieved Major Molecular Response (MMR) that is associated with a low risk of disease relapse. The invention provides a way to generate a definition of this standard in actual terms, i.e. in bcr-abl transcript copy number. The standard for bcr-abl transcript copy number is objectively determined and measurable.