<p>This invention has application in a variety of biological and biochemical fields. The invention describes a thin sheet or sheets of flexible material with surface characteristics that provide an environment for retaining biological molecules. The flexible nature of the thin sheet of material permits the use of continuous preparation, processing and analysis techniques involving more compact and less complex equipment. The invention also describes a lamination of a thin sheet of flexible material to a substantially rigid second substrate so that the combination can be processed by existing equipment. The thin sheet of flexible material may be perforated prior to lamination in order to establish distinct wells in the surface of the lamination.</p>