发明名称 |
P53 wild-type as biomarker for the treatment with mTOR inhibitors in combination with a cytotoxic agent |
摘要 |
<p>Provided are biomarkers for determining the sensitivity of proliferation diseases such as cancer to therapeutic agents, in particular mTOR inhibitors in combination with a cytotoxic agent, in particular a cytotoxic agent which damages or affects the integrity of DNA.</p> |
申请公布号 |
AU2005215910(B2) |
申请公布日期 |
2008.05.01 |
申请号 |
AU20050215910 |
申请日期 |
2005.02.22 |
申请人 |
NOVARTIS FORSCHUNGSSTIFTUNG;NOVARTIS AG |
发明人 |
GEORGE THOMAS;HEIDI LANE;TERENCE O'REILLY;ANNE BOULAY;IWAN BEUVINK |
分类号 |
C12Q1/68;G01N33/574 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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