发明名称 |
COMPOSITIONS COMPRISING VIRUSES AND METHODS FOR CONCENTRATING VIRUS PREPARATIONS |
摘要 |
Methods for purifying virus preparations are disclosed comprising (a) subjecting a virus preparation to anion-exchange chromatography, (b) adding a polyhydroxy hydrocarbon to the virus preparation of step (a), (c) increasing the concentration of virus in the virus preparation product of step (b) by applying pressure to the preparation such that diluent is removed from the virus preparation through a filter, and (d) subjecting the concentrated virus preparation product of step (c) to one or more additional processing steps. |
申请公布号 |
PL197747(B1) |
申请公布日期 |
2008.04.30 |
申请号 |
PL19990342847 |
申请日期 |
1999.02.12 |
申请人 |
SCHERING CORPORATION |
发明人 |
FREI ANDREAS;KWAN HENRY K.H.;SANDWEISS VARDA E.;VELLEKAMP GARY J.;YUEN PUI-HO;BONDOC LAUREANO L. JR;PORTER FREDERICK WILLIAM;TANG JOHN CHU-TAY;IHNAT PETER |
分类号 |
C12N7/00;A61K;A61K35/76;A61K48/00;C12N;C12N7/02;C12N15/861 |
主分类号 |
C12N7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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