摘要 |
The present invention relates to novel thiourea derivatives as a modulator for vanilloid receptor (VR) and the pharmaceutical compositions containing the same. As diseases associated with the activity of vanilloid receptor, pain acute pain, chronic pain, neuropathic pain, post-operative pain, migraine, arthralgia, neuropathies, nerve injury, diabetic neuropathy, neurodegeneration, neurotic skin disorder, stroke, urinary bladder hypersensitiveness, irritable bowel syndrome, a respiratory disorder such as asthma or chronic obstructive pulmonary disease, irritation of skin, eye or mucous membrane, fervescence, stomach-duodenal ulcer, inflammatory bowel disease and inflammatory diseases can be enumerated. The present invention provides a pharmaceutical composition for prevention or treatment of these diseases. |
申请人 |
PACIFIC CORPORATION |
发明人 |
SUH, YOUNG, GER;OH, UH, TAEK;KIM, HEE, DOO;LEE, JEE, WOO;PARK, HYEUNG, GEUN;PARK, OK, HUI;LEE, YONG, SIL;PARK, YOUNG, HO;JOO, YUNG, HYUP;CHOI, JIN, KYU;LIM, K.M.;KIM, S.Y.;KIM, JIN, KWAN;KOH, HYUN, JU;MOH, JOO, HYUN;JEONG, YEON, SU;YI, JUNG, BUM;OH, YOUNG, IM |