发明名称 |
STIMULATION, CULTURE AND PRESERVATION OF PANCREATIC AND OTHER CELLS |
摘要 |
<p>A method for stimulating pancreatic cells to synthesize and/or excrete insulin comprises contacting insulin-producing cells, in particular their aqueous suspension, with a water-soluble cellulose derivative, in particular selected from alkylated, hydroxyalkylated, and alkylated-hydroxyalkylated cellulose or a mixture thereof. A medium for the culture of pancreatic beta-cells contains an effective cell-stimulating amount of a cellulose derivative. It can be used to stimulate pancreatic beta-cells to produce and/or excrete insulin. An apparatus for such stimulation comprises a container holding a solution of a cellulose derivative in an aqueous culture medium. Stimulation of pancreatic beta-cells by a cellulose derivative is useful in the management of diabetes. Further preservative or therapeutic methods using the aqueous cellulose derivatives are disclosed.</p> |
申请公布号 |
EP0975739(B1) |
申请公布日期 |
2008.04.23 |
申请号 |
EP19980909956 |
申请日期 |
1998.03.16 |
申请人 |
ASCENDIA AB |
发明人 |
MANSSON, PER;LUNDIN, TOMAS |
分类号 |
A01N1/02;A61K9/08;A61K31/717;A61K35/39;A61P11/00;A61P11/04;A61P17/02;C07K14/62;C12N5/071;C12P21/02 |
主分类号 |
A01N1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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