发明名称 |
DIFFERENTIAL DIAGNOSTICS AND THERAPY OF VIRALLY INDUCED HEART MUSCLE DISEASE |
摘要 |
Novel polynucleotide sequences and amino acid sequences of parvovirus B19, methods for differential diagnosis of viral infection in myocardial disease and pharmaceutical compositions for the treatment thereof are disclosed. A method for the detection of a viral infection of a patient comprises the detection in a blood vessel or heart muscle tissue sample, outside of the human body, the presence or absence of Parvovirus B19 genotype 1 or Parvovirus B19 genotype 2 or Human Herpesvirus 6 or both. Similarly provided is the use of Interferon alpha in the preparation of a pharmaceutical composition for the prevention or treatment of myocardial infection by Parvovirus B19 or Human Herpesvirus 6, optionally with the addition of ribavirin. |
申请公布号 |
WO2007096199(A3) |
申请公布日期 |
2008.04.10 |
申请号 |
WO2007EP01691 |
申请日期 |
2007.02.22 |
申请人 |
IKDT INSTITUT KARDIALE DIAGNOSTIK UND THERAPIE GMBH;CHARITE-UNIVERSITAETSMEDIZIN BERLIN;LASSNER, DIRK;SCHULTHEISS, HEINZ-PETER;KUEHL, UWE |
发明人 |
LASSNER, DIRK;SCHULTHEISS, HEINZ-PETER;KUEHL, UWE |
分类号 |
C12Q1/70;A61K38/21;C07K14/015;G01N33/569 |
主分类号 |
C12Q1/70 |
代理机构 |
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