| 摘要 |
FIELD: medicine, pharmaceutical industry and technology, pharmacy. ^ SUBSTANCE: invention relates to a method for preparing a drug possessing analgesic, antipyretic and psychostimulating effect. The drug possessing analgesic, antipyretic and psychostimulating effect comprises paracetamol, propiphenazone and anhydrous caffeine as an active components, and starch, microcrystalline cellulose, magnesium stearate, copolyvidon, hydroxypropylmethylcellulose, sodium dodecyl sulfate, crospovidon and croscarmelose sodium as accessory substances taken in the definite ratio of components. Method for preparing a drug possessing analgesic, antipyretic and psychostimulating effect involves stirring sieved powders of paracetamol, propiphenazone, anhydrous caffeine and microcrystalline cellulose followed by wetting the prepared mixture with hydroxypropylcellulose solution and repeat stirring to uniform moisture distribution. Then method involves the successive granulation, drying, powdering prepared granules with a mixture of copolyvidon, dodecyl sodium sulfate, starch, croscarmelose sodium and magnesium stearate to obtain a homogenous mass followed by the tabletting process the prepared homogenous mass. The drug prepared by above described method is made as a tablet and possesses the high dissolving index and the high dosing precision. ^ EFFECT: improved preparing method of drug. ^ 3 cl, 2 tbl, 1 ex |
