PHARMACEUTICAL FORMULATION COMPRISING METFORMIN AND REPAGLINIDE
摘要
<p>The invention is related to a pharmaceutical composition comprising repaglinide in combination with metformin or a salt thereof in unit dosage form wherein a pre-formulation of the repaglinide has a pH independent dissolution profile and a relative humidity of less than about 25 % prior to mixing with the metformin or a salt thereof; and optionally one or more pharmaceutically acceptable excipients and to a method for its preparation.</p>
申请公布号
WO2008037807(A1)
申请公布日期
2008.04.03
申请号
WO2007EP60343
申请日期
2007.09.28
申请人
NOVO NORDISK A/S;HOEJGAARD, BENT;KNUDSEN, BREIAN;RASMUSSEN, STELLA, RUDKJAER;JACOBSEN, LENE, ORUP