发明名称 HETEROCYCLE-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE
摘要 Compounds having glucokinase activating effects and being useful as treatments for diabetes, which are represented by the following formula (I): (wherein X 1 to X 4 represent a carbon atom, etc., ring A represents a 5- or 6-membered heteroaryl having from 1 to 4 hetero atoms selected from the group consisting of a nitrogen atom, a sulfur atom and an oxygen atom, X 5 represent an oxygen atom, etc., X represent a carbon atom, etc., Het represents a 5- or 6-membered aliphatic hetero ring, R 1 represents aryl, etc., R 2 represents formyl, etc., R 3 represents -C 1-6 alkyl, etc.), as well as their pharmaceutically acceptable salts.
申请公布号 EP1905769(A1) 申请公布日期 2008.04.02
申请号 EP20060781274 申请日期 2006.07.12
申请人 BANYU PHARMACEUTICAL CO., LTD. 发明人 OGINO, YOSHIO;NONOSHITA,KATSUMASA;NISHIMURA, TERUYUKI;EIKI, JUN-ICHI
分类号 C07D405/14;A61K31/4439;A61K31/497;A61P3/04;A61P3/10;A61P43/00;C07D401/14;C07D409/14;C07D413/14 主分类号 C07D405/14
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