发明名称 Use of Bv8 and/or EG-VEGF to promote hematopoiesis
摘要 Disclosed is the use of Bv8 polypeptide, a polynucleotide encoding Bv8 polypeptide, EG-VEGF polypeptide, a polynucleotide encoding EG-VEGF polypeptide, or a combination thereof in the preparation of a medicament for treating an immunodeficiency disorder Also disclosed is a use of a Bv8 polypeptide antagonist, EG-VEGF polypeptide antagonist, or a combination thereof in the preparation of a medicament for treating an autoimmune disorder or a disorder associated with abnormal hematopoiesis. Also disclosed is an in vitro method for inducing proliferation of bone marrow cells, lymphoid lineage progenitor cells, or progeny thereof, comprising contacting the cells with a Bv8 polypeptide or a polynucleotide encoding Bv8 polypeptide.
申请公布号 NZ541480(A) 申请公布日期 2008.03.28
申请号 NZ20040541480 申请日期 2004.03.12
申请人 GENENTECH, INC. 发明人 FERRARA, NAPOLEONE;LECOUTER, JENNIFER
分类号 A61K38/18 主分类号 A61K38/18
代理机构 代理人
主权项
地址