发明名称 Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
摘要 One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
申请公布号 ZA200610405(B) 申请公布日期 2008.03.26
申请号 ZA20060010405 申请日期 2006.12.12
申请人 INFINITY PHARMACETICALS, INC. 发明人 ALFREDO C. CASTRO,;MICHAEL A. FOLEY,;MICHAEL J. GROGAN,;BRIAN T. HOPKINS,;DAVID A. MANN,;DENNIS J. UNDERWOOD,;LINPING ZHANG,;WEI DENG, I;CHRISTIAN C. FRITZ,;NAFEEZA HAFEEZ,;KONEY, NII O.;LISA A. MARCAURELLE,;ANDREW A. WYLIE,;KRISTOPHER M. DEPEW,;GEORGES EVANGELINOS, ASIMINA T.;EDWARD B. HOLSON,;TAO LIU,;DANIEL A. SNYDER,;LIN-CHEN YU,
分类号 A61K;A61P;C07D 主分类号 A61K
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