METHODS OF OPTIMIZING CHROMATOGRAPHIC SEPARATION OF POLYPEPTIDES
摘要
<p>Described are methods for determination of peptide specific parameter(s) of a mixture comprising a target peptide and a related impurity (or impurities) to be used in a simulation model of chromatographic separation using mathematical model(s). Also described are chromatographic simulation methods using above determined parameters, as well as computer systems and computer programs for performing one or more of the above method(s).</p>
申请公布号
WO2008028974(A1)
申请公布日期
2008.03.13
申请号
WO2007EP59432
申请日期
2007.09.08
申请人
NOVO NORDISK A/S;KIDAL, STEFFEN;HANSEN, THOMAS, BUDDE;STABY, ARNE