发明名称 |
METHOD OF DIAGNOSIS AND METHOD OF TREATMENT |
摘要 |
The present invention relates to a method for diagnosing higher susceptibility for diseases and conditions associated with low levels of AKG in a human or animal comprising the following steps: a) obtaining a biological sample from said human or animal; b) measuring the alpha-ketoglutaric acid (AKG) level in the biological sample; and c) comparing said measured AKG level with normal average AKG levels, wherein a level of AKG in said sample lower than an average level is indicative of a higher susceptibility for various diseases. Further the invention relates to a use of a substance comprising at least one member selected from the group consisting of AKG and derivates, metabolites, analogues or salts thereof for the manufacture of a pharmaceutical preparation or a food or feed supplement for the treatment or prophylaxis of diseases and conditions associated with low levels of AKG in a human or animal with low levels of AKG compared with normal average AKG levels. |
申请公布号 |
WO2007082914(A3) |
申请公布日期 |
2008.03.13 |
申请号 |
WO2007EP50499 |
申请日期 |
2007.01.18 |
申请人 |
ENTRESS AB;PIERZYNOWSKI, STEFAN |
发明人 |
PIERZYNOWSKI, STEFAN |
分类号 |
G01N33/64;A61K31/12;A61P1/00;A61P9/00;A61P13/00;A61P19/00;A61P25/00;A61P35/00 |
主分类号 |
G01N33/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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