| 发明名称 |
ANTI-CD71 MONOCLONAL ANTIBODIES AND USES THEREOF FOR TREATING MALIGNANT TUMOUR CELLS |
| 摘要 |
<p>The present invention provides novel anti-CD71 monoclonal antibodies, in particular mouse-human chimeric anti-CD71 monoclonal antibodies, advantageously associated to effector cells for triggering ADCC mechanisms. Anti-CD71 antibodies, as well as pharmaceutical compositions containing them, are useful for inhibiting proliferation and/or killing malignant tumor cells, especially metastatic cutaneous and uveal melanoma cells.</p> |
| 申请公布号 |
EP1896507(A2) |
申请公布日期 |
2008.03.12 |
| 申请号 |
EP20060795343 |
申请日期 |
2006.06.14 |
| 申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);MONOCLONAL ANTIBODIES THERAPEUTICS |
发明人 |
BOUMSELL, LAURENCE;KADOUCHE, JEAN;BENSUSSAN, ARMAND |
| 分类号 |
C07K16/28;A61K35/14;A61K39/395;A61K47/48;A61K51/10;A61M1/38;A61P35/00;A61P37/04;A61P37/06;C07K16/42;C07K16/46;C12N5/10;C12N5/20;C12N15/13;C12N15/79 |
主分类号 |
C07K16/28 |
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