<p>The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying breast cancer status in a patient. In particular, the biomarkers of this invention are useful to determine metastasis-free survival of breast cancer patients. The biomarkers can be detected by SELDI mass spectrometry in serum samples fractionated by means of anion exchange chromatography. Some of the biomarkers have been identified as: Apolipoprotein A1; Apolipoprotein A2; Haptoglobin alpha 1; Transferrin; Complement C3a; and truncated forms thereof.</p>
申请公布号
EP1896855(A2)
申请公布日期
2008.03.12
申请号
EP20060785174
申请日期
2006.06.20
申请人
BORG, JEAN-PAUL;GONCALVES, ANTHONY;MENG, XIAO-YING;FUNG, ERIC THOMAS
发明人
BORG, JEAN-PAUL;GONCALVES, ANTHONY;MENG, XIAO-YING;FUNG, ERIC THOMAS