| 发明名称 |
Thiazole derivatives having CB1-antagonistic, agonistic or partial agonistic activity |
| 摘要 |
The present invention relates to a group of thiazole derivatives which are potent antagonists, agonists or partial agonists of the cannabinoid CB1-receptor. The compounds have the general formula (I) wherein R and R1-R4 have the meanings given in the specification
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| 申请公布号 |
US7342032(B2) |
申请公布日期 |
2008.03.11 |
| 申请号 |
US20040490546 |
申请日期 |
2004.03.23 |
| 申请人 |
SOLVAY PHARMACEUTICALS, INC. |
发明人 |
LANGE JOSEPHUS H. M.;KRUSE CORNELIS G.;HERREMANS ARNOLDUS H. J.;VAN STUIVENBERG HERMAN H.;DIJKSMAN JESSICA A. R.;MCCREARY ANDREW C. |
| 分类号 |
A61K31/426;C07D277/20;A61K31/425;A61K31/427;A61K31/454;A61K31/5377;A61K31/55;A61P1/00;A61P1/04;A61P1/08;A61P1/12;A61P1/14;A61P3/04;A61P3/10;A61P7/00;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P25/00;A61P25/02;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/36;A61P27/06;A61P31/04;A61P31/12;A61P35/00;A61P41/00;A61P43/00;C07D277/56;C07D277/68;C07D417/12 |
主分类号 |
A61K31/426 |
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