发明名称 THROMBIN INHIBITING 2-OXO-1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVES
摘要 There is provided a compound of formula (I) wherein R1, R2a, R2b, R3a, R3b, R4, R5a, R5b, R6 to R8, A and G have meanings given in the description, which compounds are useful as, or are useful as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is beneficial (e.g. conditions, such as thrombo-embolisms, where inhibition of thrombin is required or desired, and/or conditions where anticoagulant therapy is indicated). ® KIPO & WIPO 2008
申请公布号 KR20080021145(A) 申请公布日期 2008.03.06
申请号 KR20087001291 申请日期 2008.01.16
申请人 ASTRAZENECA AB 发明人 NILSSON INGEMAR;POLLA MAGNUS
分类号 C07D401/12;A61K31/444 主分类号 C07D401/12
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