19-NOR-VITAMIN D ANALOGS WITH 1,2,OR 3,2 HETEROCYCLIC RING

摘要

19-nor-vitamin D analogs having an additional heterocyclic ring connecting the 3ß-oxygen and carbon-2 or the la-oxygen and carbon-2 of the A-ring of the analog, and pharmaceutical uses therefore, are described. These compounds exhibit significant activity in mobilization of bone, making them therapeutic agents for the treatment or prophylaxis of osteoporosis, osteomalacia, osteopenia, renal osteodystrophy and hypoparathyroidism.