Compounds which have activity at M1 receptor and their uses in medicine.

摘要

Compounds of formula (I) and salts and solvates are provided: wherein R⁴ is fluoro, R⁵ is selected from hydrogen, halogen, cyano, C_1-6alkyl, C_1-6alkyl substituted with one or more fluorine atoms, C_1-6alkoxy, and C_1-6alkoxy substituted with one or more fluorine atoms; and R⁶ is selected from halogen, cyano, C_1-6alkyl, C_1-6alkyl substituted with one or more fluorine atoms, C_3-6cycloalkyl, C_3-6cycloalkyl substituted with one or more fluorine atoms, C_1-6alkoxy and C_1-6alkoxy substituted with one or more fluorine atoms, and Q is hydrogen or C_1-6alkyl. The compounds are expected to be useful for therapy, for example in the treatment of psychotic disorders and cognitive impairment.