The use of moxonidine salts for purification of moxonidine
摘要
<p>The present invention provides crystalline Moxonidine salts e.g., mono-Moxonidine oxalate and mono-Moxonidine formate. Also provided by the present invention is a novel purification process of Moxonidine using these crystalline Moxonidine salts. By precipitating a Moxonidine salt from the reaction mixture and reacting it with a base, highly pure crystalline Moxonidine base is obtained in high yield.</p>
申请公布号
EP1894927(A1)
申请公布日期
2008.03.05
申请号
EP20060018236
申请日期
2006.08.31
申请人
CHEMAGIS LTD.
发明人
NADDAKA, VLADIMIR;KLOPFER, EYAL;SAEED, SHADY;ADIN, ITAI;IUSTAIN, CARMEN;ARAD, ODED;KASPI, JOSEPH