发明名称 RADIOACTIVE DIAGNOSTIC IMAGING AGENT
摘要 <p>It is intended to provide a radioactive diagnostic imaging agent comprising a radioactive halogen-labeled compound as an active ingredient, in which the active ingredient is prevented from radiolysis and its stability is improved. This is achieved by adding a biologically-acceptable sugar or sugar alcohol to the radioactive diagnostic imaging agent in an amount effective to prevent radiolysis. The amount of the sugar or sugar alcohol to be added is preferably 10 (mmol/L)/GBq/mL or more, and more preferably 50 (mmol/L)/GBq/mL or more. The sugar is preferably selected from the group consisting of erythrose, threose, ribose, arabinose, xylose, lyxose, allose, altrose, glucose, mannose, gulose, idose, galactose, talose, erythrulose, ribulose, xylulose, psicose, fructose, sorbose, and tagatose. The sugar alcohol is preferably selected from the group consisting of erythritol, xylitol, sorbitol, and mannitol.</p>
申请公布号 EP1894577(A1) 申请公布日期 2008.03.05
申请号 EP20060766486 申请日期 2006.06.08
申请人 NIHON MEDI-PHYSICS CO., LTD. 发明人 SHIMADA, TAKAYUKI;NAKATANI, AKIRA;TAKAHASHI, KEIETSU
分类号 A61K51/00;G01T1/161 主分类号 A61K51/00
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