| 发明名称 |
Identification of a JAK2 mutation involved in polycythaemia vera |
| 摘要 |
<p>An isolated JAK2 (Janus kinase 2) protein is a mutation of the amino acid 617, and especially mutation V617F, with its sequence present in SEQ ID No. 1, or a similar sequence in other mammals, is new. The nucleotide sequence coding for the variant JAK2 V617F is especially SEQ ID No 2 possessing the t/g mutation in position 1849 from the ATG marking the start of the transcription.</p> |
| 申请公布号 |
EP1895000(A1) |
申请公布日期 |
2008.03.05 |
| 申请号 |
EP20070118874 |
申请日期 |
2005.10.26 |
| 申请人 |
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS;INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE);INSTITUT GUSTAVE ROUSSY;UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES;UNIVERSITE PARIS SUD |
发明人 |
VAINCHENKER, WILLIAM;UGO, VALERIE;JAMES, CHLOE;LE COUEDIC, JEAN-PIERRE;CASADEVALL, NICOLE |
| 分类号 |
C12N9/12;C12Q1/68;G01N33/53 |
主分类号 |
C12N9/12 |
| 代理机构 |
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