| 发明名称 |
Diamino-pyrimidines and their use as angiogenesis inhibitors |
| 摘要 |
Benzimidazole derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
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| 申请公布号 |
US7338959(B2) |
申请公布日期 |
2008.03.04 |
| 申请号 |
US20040506447 |
申请日期 |
2004.09.01 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
CHAMBERLAIN STANLEY DAWES;CHEUNG MUI;EMERSON HOLLY KATHLEEN;JOHNSON NEIL W.;NAILOR KRISTEN ELIZABETH;SAMMOND DOUGLAS MCCORD;SEMONES MARCUS |
| 分类号 |
C07D239/48;A61K31/4184;A61K31/506;A61K31/5377;A61K45/00;A61P9/10;A61P9/14;A61P29/00;A61P35/00;A61P43/00;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D409/14;C07D413/14 |
主分类号 |
C07D239/48 |
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