摘要 |
The invention refers to medicine, in particular to the gynecologic oncology. Summary of the method of differentiated treatment of endometrial cancer consists in that it is determined the stage of disease, the degree of difference, the level of myometrium invasion, it is determined the level of tryptophanhydroxylase-1. Where the level of tryptophanhydroxylase-1 is above 13,8 conventional units, and to the patients is established the stage of disease IA, IB, the degree of difference 1, 2 and 3, the level of myometrium invasion under 50% or the stage IC, the degree of difference 1 and 2 and the level of myometrium invasion above 50%, it is carried out the total hysterectomy with bilateral salpingo-oophorectomy. Where the level of tryptophanhydroxylase-1 varies from 3,6 up to 13,8 conventional units, after hysterectomy, there are additionally prescribed two courses of chemotherapy with Cysplatinum û 100 mg/m2, drop-by-drop during 4 hours, once to the course and concomitantly it is prescribed the hormonotherapy with Depo-provera û 500 mg, intramuscularly, once a week and the antiestrogentherapy with Tamoxifen û 20 mg/day, the course constituting 3 months with an interval of 3 weeks between courses.
|