PHARMACEUTICAL COMPOSITION CONTAINING DULOXETIN AND BETA-3-ADRENOCEPTOR AGONIST FOR TREATMENT OF BLADDER DYSFUNCTION

摘要

The invention relates to a novel pharmaceutical combination for the treatment of bladder dysfunction, said combination comprising a serotonin and/or norepinephrine reuptake inhibitor Duloxetin and a beta-3-adrenoceptor agonist, (-) -ethyl-2-[4-(2-{[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl) -1-methylethyl]amino}ethyl) -2,5-dimethylphenyloxy]acetate and/or (-) -2-[4-(2-{[(1S,2R)-2- hydroxy-2-(4- hydroxyphenyl) -1- methylethyl]amino}ethyl) -2,5- dimethylphenyloxy] acetic acid and/or their pharmacologically acceptable salt and/or enantiomer.